Facilities / Research

Multi-center study: Innovative Control of ambient air quality in multiple IVF laboratories is associated with statistically significant improvements in clinical outcomes – analysis of 5319 cycles.

An independent multi-center peer-reviewed study published in Fertility and Sterility, Volume 106, Issue 3 Supplement, 2016, examining the impact of innovative ambient air quality control on clinical outcomes across multiple IVF laboratories. The study analyzed 5,319 IVF cycles across multiple independent fertility programs and documented a statistically significant 14.9 percentage point increase in ongoing pregnancy rates across all age groups in laboratories using LifeAire’s air quality control technology compared to controls. This independent, externally authored study — conducted entirely by IVF clinicians and scientists with no affiliation to LifeAire — represents the foundational clinical evidence supporting LifeAire’s effectiveness in IVF settings and is the most-cited IVF outcome study in LifeAire’s published research library. Published in Fertility and Sterility, 2016; 106(3 Suppl):e27-e28. Authors: Palter, S.; DiPaola, K.; Sparks, A.E.; Degelos, S.; Koulianos, G.T.; Young, J.; Halicigil, C.; Yalcinkaya, T.; She, E.; Bartolucci, A.

Research

Statistically significant improvements in clinical outcomes using engineered molecular media and genomically modeled ultraviolet light for comprehensive control of Ambient Air (AA) quality.

A peer-reviewed conference abstract published in Fertility and Sterility, Volume 102, 2014, examining the impact of LifeAire’s Aire~IVF air purification system on clinical outcomes in 1,245 non-donor IVF patients across three fertility programs over 24 months. The study evaluated the effect of comprehensive ambient air quality control — using engineered molecular media and genomically modeled ultraviolet light — on key IVF outcome metrics. Results demonstrated statistically significant improvements in implantation rate, clinical pregnancy rate, ongoing pregnancy rate, and blastocyst conversion rate following system installation, with blastocyst conversion rate increasing from 57.1% to 67.6%. The findings confirm that controlling airborne pathogens and improving ambient air quality are critical factors in optimizing embryogenesis outcomes. Published in Fertility and Sterility, 2014; 102:e91. DOI: 10.1016/j.fertnstert.2014.07.307. Authors: Forman, M.; Sparks, A.E.T.; Degelos, S.; Koulianos, G.; Worrilow, K.C.