Bi-Polar Ionization (BPI) Air Purification Systems and ASHRAE Standard 241: What You Need to Know

Achieving compliance with Standard 241—and protecting building occupants from contagious contaminants like COVID-19—takes more than a BPI air cleaning system. Read on to learn why BPI solutions must be enhanced with additional air purification technologies to safeguard occupants and enable compliance with the new standard.

germicidal ultraviolet light inactivate coronavirus N95 respirator PPE

Effectiveness of germicidal ultraviolet light to inactivate coronavirus on personal protective equipment to reduce nosocomial transmission

A peer-reviewed laboratory study published in Infection Control and Hospital Epidemiology examining the effectiveness of germicidal ultraviolet light to inactivate human coronaviruses on N95 respirators, supporting safe PPE reuse. Researchers tested two commercially available portable GUV devices — including a LifeAire Systems unit — against three coronaviruses: HCoV-229E, HCoV-OC43, and SARS-CoV-2. GUV treatment achieved average viral titer reductions of 5-log for HCoV-229E, 3-log for HCoV-OC43, and 5-log for SARS-CoV-2 on respirator surfaces. The findings confirm that LifeAire’s GUV technology is effective at decontaminating N95 respirators from human coronaviruses, supporting its potential to reduce nosocomial transmission. Published in Infection Control and Hospital Epidemiology, June 2021. Authors: Camargo, C.; Lupien, A.; McIntosh, F.; Menzies, D.; Behr, M.A.; Sagan, S.M.

Economic Effects of Air Purification Technology on Healthcare-Acquired Infection Costs: A Study of Simulated Implementation across Low-and-Middle-Income Regions of the Globe

A peer-reviewed study published in the International Journal of Academic Medicine examining the economic effects of advanced air purification technology on healthcare-acquired infection costs through simulated implementation across low- and middle-income regions of the globe. The study models the potential financial impact of deploying LifeAire-class air purification technology in healthcare facilities across diverse economic contexts, demonstrating the broader global applicability of the infection control and cost reduction outcomes documented in U.S.-based clinical studies. Published in International Journal of Academic Medicine, Volume 7, 2021, pages 285-286. Authors: Kelley, K.C.; Schlener, S.D.; Levicoff, L.; Stawicki, S.P.

Novel In-Line Gas Filter Demonstrates Improved Blastocyst Development and Extended Service Life – A Multi-Center Study.

An independent multicenter prospective randomized trial published in Fertility and Sterility comparing blastocyst development outcomes using two commercially available in-line gas filters for IVF incubators across four independent laboratories over a six-month period. The study compared the Aire~LifeLine in-line gas filter against the CODA Xtra filter, with pronuclear embryos cultured to Days 5 and 6 using laboratory-specific protocols. Results demonstrated improved blastocyst development rates with the Aire~LifeLine, as well as extended filter service life. The study provides independent, third-party evidence supporting the clinical effectiveness of the Aire~LifeLine for IVF incubator gas filtration. Published in Fertility and Sterility, 2021. Authors: Alouf, C.A.; Milette, B.; Chang, T.A.; Degelos, S.; Celia, G.

comprehensive air purification patient length of stay hospital economics

The impact of comprehensive air purification on patient duration of stay, discharge outcomes, and health care economics: A retrospective cohort study

A peer-reviewed, IRB-approved retrospective cohort study examining the impact of comprehensive air purification on patient length of stay, discharge outcomes, and healthcare economics at St. Luke’s University Health Network. The study compared 8,255 patients across a LifeAire-protected medical-surgical unit and a HEPA-only control unit over 12 months. Documented outcomes in the LifeAire-protected unit included a 39.5% reduction in patient length of stay, improved discharge metrics, and 23% cost savings per patient bed. The study confirms a direct relationship between advanced air purification and measurable improvements in both clinical and economic hospital performance. Published in Surgery, September 2020. Authors: Stawicki, S.P.; Wolfe, S.; Brisendine, C.; Eid, S.; Zangari, M.; Ford, F.; Snyder, B.; Moyer, W.; Levicoff, L.; Burfeind, W.R.

The impact of comprehensive air purification on patient duration of stay, discharge outcomes, and health care economics

The Impact of Comprehensive and Live Air Purification on Health Resource Utilization (HRU)​

A conference abstract presented at the Academic Surgical Congress examining the impact of comprehensive and live air purification on health resource utilization in an acute care hospital setting. The abstract presents findings from the St. Luke’s University Health Network research team — the same team whose full 12-month retrospective cohort study of 8,255 patients was subsequently published in the journal Surgery in September 2020. The data examines the relationship between advanced air purification and measurable improvements in patient length of stay, discharge outcomes, and healthcare economics. Presented at the Academic Surgical Congress, 2020. Authors: Wolfe, S.; Brisendine, C.; Levicoff, L.; Eid, S.; Zangari, M.; Ford, F.; Snyder, B.; Moyer, W.; Stawicki, S.P.

The Effects of Air Purification Technology on Clinical and Economic Outcomes

A conference presentation delivered at the Keystone Chapter of the American College of Surgeons Annual Meeting, 2019, examining the effects of LifeAire’s advanced air purification technology on clinical and economic outcomes in an acute care hospital setting. The presentation represents early findings from the St. Luke’s University Health Network research program that culminated in the full 12-month retrospective cohort study of 8,255 patients published in the journal Surgery in September 2020, documenting a 39.5% reduction in patient length of stay, trending reduction in HAIs, and 23% improvement in per-bed economics. Presented at the Keystone Chapter, American College of Surgeons Annual Meeting, 2019.

Multi-center study: Innovative Control of ambient air quality in multiple IVF laboratories is associated with statistically significant improvements in clinical outcomes – analysis of 5319 cycles.

An independent multi-center peer-reviewed study published in Fertility and Sterility, Volume 106, Issue 3 Supplement, 2016, examining the impact of innovative ambient air quality control on clinical outcomes across multiple IVF laboratories. The study analyzed 5,319 IVF cycles across multiple independent fertility programs and documented a statistically significant 14.9 percentage point increase in ongoing pregnancy rates across all age groups in laboratories using LifeAire’s air quality control technology compared to controls. This independent, externally authored study — conducted entirely by IVF clinicians and scientists with no affiliation to LifeAire — represents the foundational clinical evidence supporting LifeAire’s effectiveness in IVF settings and is the most-cited IVF outcome study in LifeAire’s published research library. Published in Fertility and Sterility, 2016; 106(3 Suppl):e27-e28. Authors: Palter, S.; DiPaola, K.; Sparks, A.E.; Degelos, S.; Koulianos, G.T.; Young, J.; Halicigil, C.; Yalcinkaya, T.; She, E.; Bartolucci, A.